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Symbol
Name
ID

Npy1r
neuropeptide Y receptor Y1
MGI:104963

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

decreased transitional stage B cell number

decreased mature B cell number

decreased marginal zone B cell number

decreased B cell number

abnormal T cell number

increased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

increased single-positive T cell number

abnormal spleen morphology

small spleen

abnormal splenic cell ratio

abnormal immunoglobulin level

increased IgA level

decreased IgG2a level

increased IgG2b level

increased IgM level

increased immunoglobulin level

abnormal T-helper 1 physiology

abnormal T cell activation

abnormal macrophage physiology

decreased circulating interleukin-12 level

decreased circulating tumor necrosis factor level

abnormal immune system organ morphology

abnormal lymph node cell ratio

abnormal immune system physiology

abnormal professional antigen presenting cell physiology

decreased susceptibility to type IV hypersensitivity reaction

abnormal immune cell physiology

decreased interferon-gamma secretion

abnormal inflammatory response

Availability

Mouse Genotype

Npy1r^tm1.1Wpg/Npy1r^tm1.1Wpg

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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